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1

Feasibility and results of a randomised pilot-study of a work rehabilitation programme

Meyer, Kathrin, Fransen, Jaap, Huwiler, Hansjörg, Uebelhart, Daniel, Klipstein, Andreas

Journal:

Journal of Back and Musculoskeletal Rehabilitation

Year:

2005

Language:

english

File:

PDF, 79 KB

english, 2005

2

Small Peptides Able to Suppress Prostaglandin E2 Generation in Renal Mesangial Cells

Vasilakaki, Sofia, Pastukhov, Oleksandr, Mavromoustakos, Thomas, Huwiler, Andrea, Kokotos, George

Journal:

Year:

2018

Language:

english

File:

PDF, 4.73 MB

english, 2018

3

Tiefgreifende Hangdeformation am sÃ¼dlichen Heinzenberg

Osten, Julian, KÃ¼ppers, Jan, Dufresne, Anja, Huwiler, Andreas, Amann, Florian

Journal:

Geomechanics and Tunnelling

Year:

2020

File:

PDF, 3.06 MB

2020

4

Endocrinology of Breat Cancer

Journal:

Cell Biology International

Year:

2000

Language:

english

File:

PDF, 39 KB

english, 2000

5

Targeting the conversion of ceramide to sphingosine 1-phosphate as a novel strategy for cancer therapy

Andrea Huwiler, Uwe Zangemeister-Wittke

Journal:

Critical Reviews in Oncology/Hematology

Year:

2007

Language:

english

File:

PDF, 326 KB

english, 2007

6

Identification of ceramide targets in interleukin-1 and tumor necrosis factor-alpha signaling in mesangial cells

Pfeilschifter, Josef, Huwiler, Andrea

Journal:

Kidney International

Year:

1998

Language:

english

File:

PDF, 307 KB

english, 1998

7

Changing gears in the course of glomerulonephritis by shifting superoxide to nitric oxide-dominated chemistry

Pfeilschifter, Josef, Beck, Karl-Friedrich, Eberhardt, Wolfgang, Huwiler, Andrea

Journal:

Kidney International

Year:

2002

Language:

english

File:

PDF, 102 KB

english, 2002

8

Cross-talk between nitric oxide and superoxide determines ceramide formation and apoptosis in glomerular cells

Pautz, Andrea, Franzen, Rochus, Dorsch, Simone, Boddinghaus, Boris, Briner, Verena A., Pfeilschifter, Josef, Huwiler, Andrea

Journal:

Kidney International

Year:

2002

Language:

english

File:

PDF, 778 KB

english, 2002

9

Involvement of the ABC-transporter ABCC1 and the sphingosine 1-phosphate receptor subtype S1P3in the cytoprotection of human fibroblasts by the glucocorticoid dexamethasone

Barbara Nieuwenhuis, Anja Lüth, Jerold Chun, Andrea Huwiler, Josef Pfeilschifter, Monika Schäfer-Korting, Burkhard Kleuser

Journal:

Journal of Molecular Medicine

Year:

2009

Language:

english

File:

PDF, 299 KB

english, 2009

10

Sphingosine kinase 1 is critically involved in nitric oxide-mediated human endothelial cell migration and tube formation

Stephanie Schwalm, Josef Pfeilschifter, Andrea Huwiler

Journal:

British Journal of Pharmacology

Year:

2010

Language:

english

File:

PDF, 651 KB

english, 2010

11

Loss of sphingosine kinase-1 in carcinoma cells increases formation of reactive oxygen species and sensitivity to doxorubicin-induced DNA damage

Andrea Huwiler, Nataliya Kotelevets, Cuiyan Xin, Oleksandr Pastukhov, Josef Pfeilschifter, Uwe Zangemeister-Wittke

Journal:

British Journal of Pharmacology

Year:

2011

Language:

english

File:

PDF, 1.43 MB

english, 2011

12

Feedback regulation of extracellular ATP-stimulated phosphoinositide hydrolysis by protein kinase C-α in bovine glomerular endothelial cells

Huwiler, Andrea, Briner, Verena A, Fabbro, Doriano, Pfeilschifter, Josef

Journal:

Kidney International

Year:

1997

Language:

english

File:

PDF, 928 KB

english, 1997

13

Stimulation by extracellular ATP and UTP of the stress-activated protein kinase cascade in rat renal mesangial cells

Andrea Huwiler, Gerda Van Rossum, Markus Wartmann, Josef Pfeilschifter

Journal:

British Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 550 KB

english, 1997

14

Extracellular nucleotides activate the p38-stress-activated protein kinase cascade in glomerular mesangial cells

Andrea Huwiler, Markus Wartmann, Henk Van Den Bosch, Josef Pfeilschifter

Journal:

British Journal of Pharmacology

Year:

2000

Language:

english

File:

PDF, 367 KB

english, 2000

15

Extracellular ATP and UTP activate the protein kinase B/Akt cascade via the P2Y2 purinoceptor in renal mesangial cells

Andrea Huwiler, Waltraud Rölz, Simone Dorsch, Shuyu Ren, Josef Pfeilschifter

Journal:

British Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 326 KB

english, 2002

16

Interleukin-1β inhibits ATP-induced protein kinase B activation in renal mesangial cells by two different mechanisms: the involvement of nitric oxide and ceramide

Waltraud Rölz, Cuiyan Xin, Shuyu Ren, Josef Pfeilschifter, Andrea Huwiler

Journal:

British Journal of Pharmacology

Year:

2003

Language:

english

File:

PDF, 249 KB

english, 2003

17

Heterologous desensitization of the sphingosine-1-phosphate receptors by purinoceptor activation in renal mesangial cells

Cuiyan Xin, Shuyu Ren, Josef Pfeilschifter, Andrea Huwiler

Journal:

British Journal of Pharmacology

Year:

2004

Language:

english

File:

PDF, 254 KB

english, 2004

18

The immunomodulator FTY720 and its phosphorylated derivative activate the Smad signalling cascade and upregulate connective tissue growth factor and collagen type IV expression in renal mesangial cells

Cuiyan Xin, Shuyu Ren, Wolfgang Eberhardt, Josef Pfeilschifter, Andrea Huwiler

Journal:

British Journal of Pharmacology

Year:

2006

Language:

english

File:

PDF, 273 KB

english, 2006

19

Angiotensin II stimulation of phospholipase D in rat renal mesangial cells is mediated by the AT1 receptor subtype

Josef Pfeilschifter, Andrea Huwiler, Claire Merriweather, Vreny A. Briner

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1992

Language:

english

File:

PDF, 595 KB

english, 1992

20

Protein kinase C inhibitors potentiate angiotensin II-induced phosphoinositide hydrolysis and intracellular Ca2+ mobilization in renal mesangial cells

Martin Ochsner, Andrea Huwiler, Thomas Fleck, Josef Pfeilschifter

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1993

Language:

english

File:

PDF, 605 KB

english, 1993

21

De novo ceramide biosynthesis is associated with resveratrol-induced inhibition of ornithine decarboxylase activity

Sandra Ulrich, Andrea Huwiler, Stefan Loitsch, Helmut Schmidt, Jürgen M. Stein

Journal:

Biochemical Pharmacology

Year:

2007

Language:

english

File:

PDF, 1.01 MB

english, 2007

22

New players on the center stage: Sphingosine 1-phosphate and its receptors as drug targets

Andrea Huwiler, Josef Pfeilschifter

Journal:

Biochemical Pharmacology

Year:

2008

Language:

english

File:

PDF, 224 KB

english, 2008

23

Cis-4-methylsphingosine is a sphingosine-1-phosphate receptor modulator

Michael ter Braak, Ralf Frederik Claas, Bianca Hegen, Sandra Labocha, Nerea Ferreirós, Josef Pfeilschifter, Andrea Huwiler, Gerhild van Echten-Deckert, Dagmar Meyer zu Heringdorf

Journal:

Biochemical Pharmacology

Year:

2011

Language:

english

File:

PDF, 823 KB

english, 2011

24

The sphingosine kinase 1 and S1P1 axis specifically counteracts LPS-induced IL-12p70 production in immune cells of the spleen

Matthias Schröder, Cornelia Richter, Martina Herrero San Juan, Katrin Maltusch, Oliver Giegold, Gianluca Quintini, Josef M. Pfeilschifter, Andrea Huwiler, Heinfried H. Radeke

Journal:

Molecular Immunology

Year:

2011

Language:

english

File:

PDF, 1003 KB

english, 2011

25

Lipids as targets for novel anti-inflammatory therapies

Andrea Huwiler, Josef Pfeilschifter

Journal:

Pharmacology & Therapeutics

Year:

2009

Language:

english

File:

PDF, 944 KB

english, 2009

26

Effects of high glucose on cytokine-induced nerve growth factor (NGF) expression in rat renal mesangial cells

Klaus Heese, Karl-Friedrich Beck, Meik Helmut Behrens, Katharina Plüss, Wolfgang Fierlbeck, Andrea Huwiler, Heiko Mühl, Helmut Geiger, Uwe Otten, Josef Pfeilschifter

Journal:

Biochemical Pharmacology

Year:

2003

Language:

english

File:

PDF, 459 KB

english, 2003

27

Nitric oxide and mechanisms of redox signalling: matrix and matrix-metabolizing enzymes as prime nitric oxide targets

Josef Pfeilschifter, Wolfgang Eberhardt, Andrea Huwiler

Journal:

European Journal of Pharmacology

Year:

2001

Language:

english

File:

PDF, 339 KB

english, 2001

28

Interleukin-1 inhibits angiotensin II-stimulated protein kinase B pathway in renal mesangial cells via the inducible nitric oxide synthase

Waltraud Rölz, Cuiyan Xin, Shuyu Ren, Josef Pfeilschifter, Andrea Huwiler

Journal:

European Journal of Pharmacology

Year:

2002

Language:

english

File:

PDF, 427 KB

english, 2002

29

Nitric oxide augments release of chemokines from monocytic U937 cells: modulation by anti-inflammatory pathways

Heiko Mühl, Jae-Hyung Chang, Andrea Huwiler, Markus Bosmann, Jens Paulukat, Rajko Ninic, Marcel Nold, Markus Hellmuth, Josef Pfeilschifter

Journal:

Free Radical Biology and Medicine

Year:

2000

Language:

english

File:

PDF, 294 KB

english, 2000

30

A role for protein kinase C-α in zymosan-stimulated eicosanoid synthesis in mouse peritoneal macrophages

Andrea HUWILER, Josef PFEILSCHIFTER

Journal:

Year:

1993

Language:

english

File:

PDF, 941 KB

english, 1993

31

Distinct Signaling Pathways Mediate Phorbol-Ester-Induced and Cytokine-Induced Inhibition of Erythropoietin Gene Expression

Joachim Fandrey, Andrea Huwiler, Stilla Frede, Josef Pfeilschifter, Wolfgang Jelkmann

Journal:

Year:

1994

Language:

english

File:

PDF, 707 KB

english, 1994

32

Platelet-derived Growth Factor Stimulates de-Novo Synthesis of Mitogen-activated Protein Kinase in Renal Mesangial Cells

Andrea Huwiler, Doriano Fabbro, Josef Pfeilschifter

Journal:

Year:

1995

Language:

english

File:

PDF, 554 KB

english, 1995

33

Protein Kinase C Phosphorylates and Activates GTP Cyclohydrolase I in Rat Renal Mesangial Cells

Christine Lapize, Christoph Plüss, Ernst R. Werner, Andrea Huwiler, Josef Pfeilschifter

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 95 KB

english, 1998

34

Nitric Oxide Stimulates Chronic Ceramide Formation in Glomerular Endothelial Cells

Andrea Huwiler, Simone Dorsch, Verena A. Briner, Henk van den Bosch, Josef Pfeilschifter

Journal:

Biochemical and Biophysical Research Communications

Year:

1999

Language:

english

File:

PDF, 215 KB

english, 1999

35

Superoxide Potently Induces Ceramide Formation in Glomerular Endothelial Cells

Andrea Huwiler, Boris Böddinghaus, Andrea Pautz, Simone Dorsch, Verena A. Briner, Volker Brade, Josef Pfeilschifter

Journal:

Biochemical and Biophysical Research Communications

Year:

2001

Language:

english

File:

PDF, 3.82 MB

english, 2001

36

Inhibition of erythropoietin production by phorbol ester is associated with down-regulation of protein kinase C-α isoenzyme in hepatoma cells

Wolfgang Jelkmann, Andrea Huwiler, Joachim Fandrey, Josef Pfeilschifter

Journal:

Biochemical and Biophysical Research Communications

Year:

1991

Language:

english

File:

PDF, 540 KB

english, 1991

37

Comparison of different tumour promoters and bryostatin 1 on protein kinase C activation and down-regulation in rat renal mesangial cells

Andrea Huwiler, Doriano Fabbro, Josef Pfeilschifter

Journal:

Biochemical Pharmacology

Year:

1994

Language:

english

File:

PDF, 2.08 MB

english, 1994

38

Protein kinase C isoenzymes in the rat retina: Immunocharacterization of calcium independent subtypes

Hans H. Jung, Andrea Huwiler, Josef Pfeilschifter, Charlotte E. Remé

Journal:

Experimental Eye Research

Year:

1992

Language:

english

File:

PDF, 180 KB

english, 1992

39

Immunocharacterization of δ- and ζ-isoenzymes of protein kinase C in rat renal mesangial cells

Andrea Huwiler, Doriano Fabbro, Silvia Stabel, Josef Pfeilschifter

Journal:

Year:

1992

Language:

english

File:

PDF, 440 KB

english, 1992

40

A role for protein kinase C-ϵ in angiotensin II stimulation of phospholipase D in rat renal mesangial cells

Josef Pfeilschifter, Andrea Huwiler

Journal:

Year:

1993

Language:

english

File:

PDF, 521 KB

english, 1993

41

Interleukin-1 stimulates de novo synthesis of mitogen-activated protein kinase in glomerular mesangial cells

Andrea Huwiler, Josef Pfeilschifter

Journal:

Year:

1994

Language:

english

File:

PDF, 445 KB

english, 1994

42

Transforming growth factor β2 stimulates acute and chronic activation of the mitogen-activated protein kinase cascade in rat renal mesangial cells

Andrea Huwiler, Josef Pfeilschifter

Journal:

Year:

1994

Language:

english

File:

PDF, 635 KB

english, 1994

43

Nitric oxide stimulates stress-activated protein kinases in glomerular endothelial and mesangial cells

Josef Pfeilschifter, Andrea Huwiler

Journal:

Year:

1996

Language:

english

File:

PDF, 442 KB

english, 1996

44

Differential binding of ceramide to MEKK1 in glomerular endothelial and mesangial cells

Andrea Huwiler, Cuiyan Xin, Anja-Kristina Brust, Verena A Briner, Josef Pfeilschifter

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2004

Language:

english

File:

PDF, 1.19 MB

english, 2004

45

Ceramide induces translocation of protein kinase C-α to the Golgi compartment of human embryonic kidney cells by interacting with the C2 domain

Armaz Aschrafi, Rochus Franzen, Soheyla Shabahang, Doriano Fabbro, Josef Pfeilschifter, Andrea Huwiler

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2003

Language:

english

File:

PDF, 1.59 MB

english, 2003

46

Inhibition of Rho modulates cytokine-induced prostaglandin E2 formation in renal mesangial cells

Claudia Petry, Gerhard Fritz, Josef Pfeilschifter, Andrea Huwiler

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2004

Language:

english

File:

PDF, 626 KB

english, 2004

47

Histamine increases sphingosine kinase-1 expression and activity in the human arterial endothelial cell line EA.hy 926 by a PKC-α-dependent mechanism

Andrea Huwiler, Frauke Döll, Shuyu Ren, Sabine Klawitter, Anna Greening, Isolde Römer, Svetlana Bubnova, Luise Reinsberg, Josef Pfeilschifter

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2006

Language:

english

File:

PDF, 794 KB

english, 2006

48

The epidermal growth factor stimulates sphingosine kinase-1 expression and activity in the human mammary carcinoma cell line MCF7

Frauke Döll, Josef Pfeilschifter, Andrea Huwiler

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2005

Language:

english

File:

PDF, 459 KB

english, 2005

49

Nephrin expression is increased in anti-Thy1.1-induced glomerulonephritis in rats

Liliana Schaefer, Shuyu Ren, Roland M. Schaefer, Daniel Mihalik, Andrea Babelova, Andrea Huwiler, Josef Pfeilschifter

Journal:

Biochemical and Biophysical Research Communications

Year:

2004

Language:

english

File:

PDF, 912 KB

english, 2004

50

Corrigendum to “Identification of the LIM kinase-1 as a ceramide-regulated gene in renal mesangial cells” [Biochem. Biophys. Res. Commun. 298 (2002) 408–413]

Soheyla Shabahang, Yan-Hong Liu, Andrea Huwiler, Josef Pfeilschifter

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

File:

PDF, 69 KB

2005